Saturated fat increases risk of Alzheimer's disease

Introducing unsaturated fats rich in vegetable oils into the diet, in the form of fish, olives and avocados, reduces the risk of developing senile dementia. This conclusion was reached by scientists who devoted several large studies to Alzheimer’s disease.

A study conducted by the University of Rovira e Virgili (URV) found a link between a diet rich in saturated fats and Alzheimer's disease. The scientists' work focused on how this type of diet affects certain molecules found in the blood and brain that act as markers and regulators of disease.

The study was led by Monica Boullo, professor in the Department of Biochemistry and Biotechnology, member of the Division of Metabolic Health and Nutrition, and the Center for Environmental, Food and Toxicology Technologies (TecnATox) at URV.

The study was conducted on mice that developed Alzheimer's disease as adults. Previous studies in these animals had already shown that mice fed a high-saturated-fat diet developed Alzheimer's disease much earlier than mice fed a normal diet.

Recent research data indicate a leading role of cholesterol in the occurrence of Alzheimer's disease. This is what causes damage to nerve cells. Men who preferred fatty and meat foods had elevated blood cholesterol levels (more than 6.5 mmol/l) and were three times more likely to suffer from dementia. Scientists recognize this disease by characteristic changes in brain tissue, as a result of which the conduction of nerve impulses is disrupted, the work of nerve cells becomes difficult and gradually becomes impossible, which after a few years leads to their gradual death. The National Research Center for Healthy Nutrition has collected the most modern approaches and basic recommendations. With their help, it was possible to identify the main patterns in the development of a serious illness and develop a systematic approach to its prevention.

Studies have shown that those whose blood contains higher levels of Omega-3, fatty acids and vitamins A, C, E, D have clear memory and a strong mind.

This shows: Concomitant intake of saturated fat and trans fat increases the risk of Alzheimer's disease by nine times. High consumption of saturated fat doubles the risk of presenile dementia, and consumption of trans fat, even in small doses, triples it. Some studies have shown that For the first signs of Alzheimer's disease to appear, it only takes two to three years to eat poorly.

“The study results are a step towards understanding this disease and may explain the link between obesity, type 2 diabetes and Alzheimer's disease. The results also open up new targets for potential prevention and treatment of the disease,” says Monica Boullo. The study provides new evidence about how a high-fat diet may affect brain health and also opens the door for future research into nutritional strategies as a treatment for Alzheimer's disease.

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