Coronavirus: MRNA vaccination may affect thyroid function

Thyroid disorders are very common and affect more than 10% of the adult population.

Autoimmune thyroiditis or Hashimoto’s goiter is a condition in which the thyroid gland is gradually destroyed. This is currently the most common problem with it and often results in subclinical or clinical hypothyroidism (underactive thyroid).

Hashimoto’s thyroiditis is a chronic autoimmune inflammation of the thyroid gland. It can be caused by a viral infection or an autoimmune disease. Hashimoto’s goiter is the most common type of thyroiditis and the most common cause of hypothyroidism. Hypothyroidism (from the Greek hypo – under (below) and lat. glandula thyreoidea – thyroid gland) is a condition caused by a long-term, persistent lack of thyroid hormones – thyroxine (T4) and triiodothyronine (T3).

After studying a study recently published in the international scientific journal Frontiers in Endocrinology, professors, doctors and specialists from the National University of Athens and Kapodistrias, as well as Alexandras Hospital, tried to answer the following questions:

What happens to patients diagnosed with autoimmune thyroiditis who were given the H-vaccine (comparison with healthy people). Whether there are changes in thyroid function after vaccination with the Pfizer/BioNTech mRNA vaccine.

The study included two additional subsections. In the first, neutralizing antibody levels after Pfizer/BioNTech mRNA vaccination were compared in 56 patients with autoimmune Hashimoto’s thyroiditis and 56 healthy subjects of the same age and sex, from the first dose to three months after the second.

In a second satellite study, thyroid hormone levels (T3, T4, TSH) and thyroid autoantibodies (anti-TG, anti-TPO) were tested before the first dose and one month after vaccination in 72 healthy individuals without a history of thyroid disease.

The Greek study showed for the first time in the international literature that patients with autoimmune thyroiditis show a similar immune response to the Pfizer/BioNTech mRNA vaccine as healthy people. However, vaccination can affect thyroid function.


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