Pfizer and Moderna: the degree of protection of the vaccinated

The forced mandatory vaccination of medical personnel with drugs from SARS-CoV-2 made it possible to assess the degree of “reliability” of Pfizer and Moderna in real conditions.

Theodore Psaltopoulou, Yiannis Danasis, Panos Malandrakis and Thanos Dimopoulos (EKPA Rector), doctors of the therapeutic clinic of the Kapodistrian National University of Athens School of Medicine, Theodore Psaltopoulou, Yannis Danasis,

Scientists conducted a study based on data from 25 centers in the United States. Positive cases were determined based on the PCR test result or antigen test for SARS-CoV-2 and at least one symptom associated with COVID-19. Subjects in the control group had a negative PCR result for SARS-CoV-2, regardless of symptoms.

Vaccination efficacy was determined both 14 days after the first dose and 6 days after the second dose (partial vaccination) and at least 7 days after the second dose (complete vaccination).

This study included 1482 positive cases of COVID-19 (patients) and 3449 people in the control group. The partial vaccination efficacy was 77.6% with BNT162b2 (Pfizer / BioNTech) and 88.9% with mRNA-1273 (Moderna).

The efficacy with complete vaccination was 88.8% with the BNT162b2 vaccine (Pfizer / BioNTech) and 96.3% with the mRNA-1273 vaccine (Moderna).

The researchers summed up the results: mRNA vaccines against SARS-CoV-2 are very effective in real-world settings for preventing COVID-19 in healthcare workers. It is especially important that protection also applies to individuals at risk of serious illness, as well as to “vulnerable” groups of people with underlying severe chronic illnesses.





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