A drug that could end the coronavirus pandemic

The final clinical trials of molnupiravir have raised high hopes for treating those already infected with the coronavirus, and it now appears to be acting prophylactically by preventing SARS-CoV-2 infection.

Today, hospitals are administering drugs to fight the disease caused by the new coronavirus, Covid-19, but the pill, developed by the American pharmaceutical company Merck, can be taken at home like any prescription antibiotic.

This drug appears to successfully suppress RNA replication of many viruses, including the new coronavirus SARS-CoV-2, as well as earlier versions such as SARS-CoV-1 and MERS.

When the coronavirus reproduces, it creates a copy of its own RNA, but this drug invades the new RNA, instructing it to self-destruct, clearing the virus from the human body.

The company announced the creation of the drug in March. Human studies are currently ongoing: the drug is administered to 202 patients with Covid-19 symptoms (outside the hospital). The viral load is reported to be significantly reduced three days after administration in patients with mild symptoms: only 2% of those who received a three-day course of 800 mcg molnupiravir still had viral load, compared with 17% of those who received placebo …

Moreover, within five days of starting treatment, all (100%) of those who received 400 or 800 micrograms of the drug completely cleared the coronavirus from their bodies, while 11% of those who took the placebo still had viral load. …

The conclusion of scientists, even before the completion of clinical trials on hospitalized patients, is that the drug not only cleanses the body of coronavirus, but also prevents its transmission.

The benefits of a successful trial of this drug and drugs based on the same active ingredient are enormous: this tablet will be enough to prevent most cases of serious illness. But it can also be used to prevent the virus from mutating, as it essentially causes it to mutate … to something stillborn, something that could be called an Omega mutation that would end the coronavirus nightmare.

Source: The Conversation

PS We have already written several times about drugs for the treatment of coronavirus, one of them, produced one Israeli company, even started test at the Athens University Hospital. But, apparently, something went wrong. Therefore, let’s not rush and rejoice until the drug shows real and lasting results, because this may turn out to be another divorce.





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